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Why would the flexibility in the responses of body in nicotinic receptors be useful?

Nicotinic receptors always produce depolarizations while muscarinic receptors may cause depolarizations or hyperpolarizations. Briefly explain why this is possible. Why would this flexibility in the responses of the body be useful?

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1. Muscarinic receptors re more sensitive to muscarine than to nicotine.Their counterparts are nicotinic acetylcholine receptors, receptor ion channels which are important in the autonomic nervous system. Many substances manipulate these two distinct receptors by acting as selective agonists or antagonists. So that's why this flexibility is useful. http://74.6.239.67/search/cache?ei=UTF-8&p=agonists+and+antagonists+receptors+flexibility&fr=ks-ans&u=courses.washington.edu/chat543/cvans/sfp/ansrec.html&w=agonists+antagonists+antagonist+receptors+receptor+flexibility&d=Oc81-xlMTIu_&icp=1&.intl=us .